DNA and Genes
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Genes are the blueprints of life. Genes control everything from hair color to blood sugar by telling cells which proteins to make, how much, when, and where. Genes exist in most cells. Inside a cell is a long strand of the chemical DNA (deoxyribonucleic acid). A DNA sequence is a specific lineup of chemical base pairs along its strand. The part of DNA that determines what protein to produce and when, is called a gene.
First established in 1985 by Sir Alec Jeffreys, DNA testing has become an increasingly popular method of identification and research. The applications of DNA testing, or DNA fingerprinting within forensic science is often what most people think of when they hear the phrase. Popularized by television and cinema, using DNA to match blood, hair or saliva to criminals is one purpose of testing DNA. It is also frequently used for other benefits, like wildlife studies, paternity testing, body identification, and in studies pertaining to human dispersion.While most aspects of DNA are identical in samples from all human beings, concentrating on identifying patterns called microsatellites reveals qualities specific and unique to the individual. During the early stages of this science, a DNA test was performed using an analysis called restriction fragment length polymorphism. Because this process was extremely time consuming and required a great deal of DNA, new methods like polymerase chain reaction and amplified fragment length polymorphism have been employed.The benefits of DNA testing are ample. In 1987, Colin Pitchfork became the first criminal to be caught as a result of DNA testing. The information provided with DNA tests has also helped wrongfully incarcerated people like Gary Dotson and Dennis Halstead reclaim their freedom.
Latest about Genetics
![an illustration of DNA](https://cdn.mos.cms.futurecdn.net/nsuheccAxLTwnth6njaFBJ-320-80.jpg)
Massive study of 3 million people reveals genetic 'hotspots' linked to bipolar disorder
By Sibani Ram published
A new study has greatly expanded the number of gene variants thought to be tied to bipolar disorder.
![An illustration of a damaged strand of DNA against a black background. The damage can be shown in red.](https://cdn.mos.cms.futurecdn.net/wXXkNxuzrUgBeZnFgQnhhj-320-80.jpg)
People with this rare genetic condition can't repair damage to their DNA
By Emily Cooke published
LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged DNA.
![A pregnant woman undergoes an ultrasound](https://cdn.mos.cms.futurecdn.net/kw2QiQSZriFM2nyzroFaoN-320-80.jpg)
IVF may raise risk of certain disorders in babies — and epigenetic 'signatures' in the placenta could explain why
By Jennifer Zieba published
Researchers identified genes that could explain why some assisted reproductive technologies, like IVF, carry a higher risk of growth and metabolic issues in offspring.
![Illustration of the structure of a protein in yellow, purple and red against a black background.](https://cdn.mos.cms.futurecdn.net/WuRyjsEj4Vmcn82Ku2ESZf-320-80.jpg)
1st-of-its-kind database reveals how DNA mutations 'destabilize' proteins, triggering genetic disease
By Emily Cooke published
A new mega-database of half a million mutations may flag new ways of treating genetic disease, scientists say.
![an illustration of DNA](https://cdn.mos.cms.futurecdn.net/hQRbURdgfDEXXjQ5yY8DJU-320-80.jpg)
How do DNA tests tell if two people are related?
By Skyler Ware published
How can DNA from a cheek swab determine if someone is closely related to you?
![Composite image of four images of a young girl with Angelman syndrome. In two of the images she is facing she camera, in another she is side on to the camera and the other image shows her hands. Behind the composite image is a blurred, enlarged version if it.](https://cdn.mos.cms.futurecdn.net/pPZMfAKB9QTi5WF2Sj697h-320-80.png)
Angelman syndrome: A disorder that stops people walking and speaking
By Emily Cooke published
Angelman syndrome is a rare disease that disrupts the normal development and function of cells, particularly in the nervous system, leading to severe developmental delays and learning disabilities.
![A person holds a grumpy-looking orange cat](https://cdn.mos.cms.futurecdn.net/xL6zy6DKV3ZuTypZQSdQrJ-320-80.jpg)
Scientists reveal genes that make cats orange
By Lluís Montoliu published
Two new studies have revealed why some cats are orange — an enduring enigma of genetics, until now.
![An illustration of DNA breaking apart into tiny pieces](https://cdn.mos.cms.futurecdn.net/VT25uCg9mWCAQNc3vMpvuP-320-80.jpg)
New CRISPR system pauses genes, rather than turning them off permanently
By Jennifer Zieba published
Researchers in Lithuania present the molecular structure of a new, more-versatile CRISPR system for gene editing.
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